Recently I was asked if it is possible to place a no_sms_on_drive.sms file on a drive where SCCM is installed.
Before I answer the question, no_sms_on_drive.sms is a simple file which you would place on a drive where you don't want SCCM files to be copied, for example distribution point files and other SCCM stuff.
In this current case there where to drives one for SCCM (C:) and second for distribution point and other related files (D:). When free space on D: was less than on C: SCCM started to place SCCM content on C:.
As I found it you can actuall place no_sms_on_drive.sms on C: drive to avoid this situation and DP files would only be copied on D:. More info here https://social.technet.microsoft.com/Forums/en-US/6eb3b472-f772-4939-9480-10d5a8a0f1a2/nosmsondrivesms-file-placement?forum=configmanagergeneral